Indication-specific dosing for Mag-Ox 400, Uro-Mag, Mag-Caps (magnesium oxide), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. (2023)

Patient Education
magnesium oxide oral

MAGNESIUM SUPPLEMENT - ORAL

(mag-NEE-zee-um)

COMMON BRAND NAME(S): Uro-Mag

USES: This medication is a mineral supplement used to prevent and treat low amounts of magnesium in the blood. Some brands are also used to treat symptoms of too much stomach acid such as stomach upset, heartburn, and acid indigestion. Magnesium is very important for the normal functioning of cells, nerves, muscles, bones, and the heart. Usually, a well-balanced diet provides normal blood levels of magnesium. However, certain situations cause your body to lose magnesium faster than you can replace it from your diet. These situations include treatment with "water pills" (diuretics such as furosemide, hydrochlorothiazide), a poor diet, alcoholism, or other medical conditions (such as severe diarrhea/vomiting, stomach/intestinal absorption problems, poorly controlled diabetes).

HOW TO USE: Take this product by mouth as directed. Follow all directions on the product package. If you have any questions, ask your doctor or pharmacist.It is best to take magnesium supplements with a meal to reduce stomach upset and diarrhea unless otherwise directed by the product instructions or your doctor.Take each dose with a full glass (8 ounces or 240 milliliters) of water unless your doctor directs you otherwise. Swallow extended-release capsules and delayed-release/enteric coated tablets or capsules whole. Do not crush or chew extended-release or delayed-release/enteric coated capsules or tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.If you are taking the chewable tablets, chew each tablet thoroughly before swallowing.If you are using a liquid product, use a medication measuring device to carefully measure the dose. Do not use a household spoon because you may not get the correct dose. If you are using a suspension, shake the bottle well before each dose.Take this medication regularly in order to get the most benefit from it. Remember to take it at the same time(s) each day. Dosage is based on your medical condition and response to treatment. Do not increase your dose or take it more often than directed on the product package or by your doctor. Too much magnesium in the blood can cause serious side effects.Tell your doctor if symptoms of low magnesium blood levels (such as muscle cramps, tiredness, irritability, depression) last or get worse. If you think you may have a serious medical problem, get medical help right away.

SIDE EFFECTS: Stomach upset and diarrhea may occur. Taking this product with a meal helps to reduce these effects. If either of these effects last or get worse, tell your doctor or pharmacist promptly.If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before taking a magnesium supplement, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.If you have the following health problem, consult your doctor or pharmacist before using this product: kidney disease.Liquids, powders, or some other forms of this product may contain sugar and/or aspartame. Liquid products may also contain alcohol. Caution is advised if you have diabetes, alcohol dependence, liver disease, phenylketonuria (PKU), or any other condition that requires you to limit/avoid these substances in your diet. Ask your doctor or pharmacist about using this product safely.During pregnancy, this product should be used only when clearly needed. Discuss the risks and benefits with your doctor.It is not known whether this product passes into breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: If you are taking this product under your doctor's direction, your doctor or pharmacist may already be aware of possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.Before using this product, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: cellulose sodium phosphate, digoxin, sodium polystyrene sulfonate.Magnesium can bind with certain medications, preventing their full absorption. If you are taking a tetracycline-type medication (such as demeclocycline, doxycycline, minocycline, tetracycline), separate the time of the dose from the time of the magnesium supplement dose by at least 2 to 3 hours. If you are taking a bisphosphonate (for example, alendronate), a thyroid medication (for example, levothyroxine), or a quinolone-type antibiotic (such as ciprofloxacin, levofloxacin), ask your doctor or pharmacist about how long you should wait between doses and for help finding a dosing schedule that will work with all your medications.Check the labels on all your prescription and nonprescription/herbal products (such as antacids, laxatives, vitamins) because they may contain magnesium. Ask your pharmacist about using those products safely.This document does not contain all possible interactions. Before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include slow heartbeat, severe drowsiness, dizziness, confusion, muscle weakness, loss of consciousness.

NOTES: Keep all regular medical and laboratory appointments. If your doctor has directed you to take this medication, laboratory and/or medical tests (such as magnesium blood levels, kidney function tests) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.Magnesium supplements are available in different forms with different amounts of magnesium. Many are available without a prescription. Ask your doctor or pharmacist for help in selecting the best product for you.Eat a well-balanced diet. Foods high in magnesium include avocados, bananas, beans, whole grain cereals, green vegetables, and nuts.

MISSED DOSE: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

STORAGE: Store at room temperature away from light and moisture. Refer to the product package for details. Do not store in the bathroom. If you have any questions about storage, ask your pharmacist. Keep all drug products away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

Information last revised March 2022. Copyright(c) 2022 First Databank, Inc.

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

FAQs

What is Mag Ox 400 mg used for? ›

This medication is a mineral supplement used to prevent and treat low amounts of magnesium in the blood. Some brands are also used to treat symptoms of too much stomach acid such as stomach upset, heartburn, and acid indigestion.

What does Mag ox do for the body? ›

Magnesium oxide is a form of magnesium commonly taken as a dietary supplement. It has a lower bioavailability than other forms of magnesium, but it may still offer benefits. Mainly, it's used to treat migraine and constipation. It may also help reduce blood pressure, blood sugar, and anxiety in certain populations.

When should I take Mag Ox 400? ›

Take this medicine with a full glass of water. When using this medicine as a laxative, it may be best to take your dose at bedtime. Magnesium oxide may be taken with food if it upsets your stomach. Call your doctor if your symptoms do not improve after 7 days of treatment, or if symptoms get worse.

Who should not take magnesium? ›

People with diabetes, intestinal disease, heart disease or kidney disease should not take magnesium before speaking with their health care provider. Overdose. Signs of a magnesium overdose can include nausea, diarrhea, low blood pressure, muscle weakness, and fatigue. At very high doses, magnesium can be fatal.

What is the best magnesium for anxiety and depression? ›

Based on current data, magnesium taurate and glycinate have the most research supporting their effects on anxiety and other mental health disorders. Magnesium malate and threonine have also demonstrated therapeutic effects and may be useful in many psychiatric cases.

Which is better to take magnesium or magnesium oxide? ›

Magnesium oxide is best used for digestive problems and heartburn. Magnesium oxide can also be used to supplement magnesium levels in the body, but it may not work as well as other magnesium compounds that are more readily absorbed into the bloodstream, including those you can get naturally from foods.

What kind of magnesium should I take for leg cramps? ›

Magnesium citrate may be the most effective type if you want to try a supplement. If you're magnesium deficient, there may be other benefits from increasing your intake of this nutrient. And other remedies are available for leg cramping that may help.

Does magnesium oxide lower blood pressure? ›

The administration of magnesium oxide (400 mg daily) for eight weeks in patients with hypertension can reduce blood pressure levels, and this reduction has already been detected in office measurements and by ambulatory blood pressure monitoring [29].

How do you know if your magnesium is low? ›

How is magnesium deficiency diagnosed? Magnesium deficiency is diagnosed via a blood test and sometimes a urine test. Your doctor may order the blood test if you have symptoms such as weakness, irritability, abnormal heart rhythm, nausea and/or diarrhoea, or if you have abnormal calcium or potassium levels.

Does magnesium before bed help you sleep? ›

Magnesium for sleep

Some studies have found that magnesium supplements can: Make it easier to fall asleep. Improve sleep quality. Reduce symptoms of restless legs syndrome, which can interfere with a good night's sleep.

Does magnesium oxide help with anxiety? ›

Magnesium oxide is a magnesium salt that is used to treat constipation, heartburn, high blood pressure, type 2 diabetes, migraines, muscle pain, and anxiety.

Is magnesium oxide good for sleep? ›

Avoid magnesium oxide, which is a stool softener and probably much less helpful for your insomnia. Dr. Umeda recommends taking the supplement about 30 minutes before bedtime. And don't take more than the recommended amount.

How much mag ox can you take? ›

The recommended dose for MagOx is 2 tablets per day. You may only need to take 1 tablet a day.

Why do doctors prescribe magnesium? ›

Magnesium helps maintain a normal heart rhythm and doctors sometimes administer it intravenously (IV) in the hospital to reduce the chance of atrial fibrillation and cardiac arrhythmia (irregular heartbeat). People with congestive heart failure (CHF) are often at risk for developing cardiac arrhythmia.

Does magnesium before bed help you sleep? ›

Magnesium helps the body relax. This nutrient reduces stress and helps you sleep longer. In contrast, melatonin helps you get to sleep faster. Both magnesium and melatonin can be used to treat insomnia, sometimes even in combination.

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